HHS Shines Highlight on Diagnostic Innovation Throughout Lyme Illness


As we mark Lyme Illness Consciousness Month this Could, HHS is proud to rejoice the 10 groups collaborating in Part 2 of the LymeX Diagnostics Prize. The final word objective of HHS and the Steven & Alexandra Cohen Basis’s LymeX Innovation Accelerator (LymeX) competitors is to nurture the event of diagnostics towards Meals and Drug Administration evaluation.

The present two-tier antibody testing system—initially developed in 1994 for illness surveillance, not as a stand-alone diagnostic take a look at—depends on the presence of antibodies and might solely be used precisely 4 to 6 weeks after the affected person turns into contaminated.

Accelerating innovation by money prizes and professional sources

Via September 2023, ten groups are collaborating within the Part 2 digital accelerator, which gives entry to digital studying, mentorship, biorepository subject material experience, and networking alternatives. With prior work in areas starting from sepsis to genetic sequencing and glycomics, the accelerator cohort is making use of a broad vary of experience to their proposed next-generation diagnostics.

Through the use of a prize competitors mannequin, the LymeX Diagnostics Prize gives money prizes alongside a variety of non-monetary sources. The competitors is designed to stimulate the marketplace for Lyme illness diagnostics by serving to entrants overcome diagnostic growth boundaries with prize funds and technical help—whereas additionally fostering cross-disciplinary collaboration.

Bettering testing accessibility is necessary to enhancing affected person outcomes, and groups are already starting to think about the problem with the assistance of scientific research and system design sources. Over the summer season, the cohort will take part in roundtable discussions with sufferers and clinicians as they refine their ideas.

The LymeX Diagnostics Prize is setting a brand new bar for innovation in illness diagnostics. If checks are efficiently validated, the cohort’s work may assist enhance Lyme illness remedy total—in addition to checks for different infectious illnesses.

Wanting forward: Professional judging panel to convene in October 2023

Following the accelerator, the cohort will submit idea papers that element answer refinement, scientific and affected person enter, and a roadmap from lab to market.

The competitors judging panel—composed of consultants throughout biology, scientific and expertise translation, affected person expertise and advocacy, diagnostic science and expertise, exponential innovation, and ethics—will consider eligible submissions based on official Part 2 analysis standards. Primarily based on the judges’ evaluations, they are going to suggest as much as 5 Part 2 winners of the LymeX Diagnostics Prize.

The Steven & Alexandra Cohen Basis has made a beneficiant $10 million pledge to the LymeX Diagnostics Prize. HHS and the Steven & Alexandra Cohen Basis awarded $1 million in Part 1 of the LymeX Diagnostics Prize, with $9 million in extra LymeX prizes projected to be accessible in future phases, together with Part 2. A choice of accelerator sources will probably be made accessible to the general public on the competitors web site to assist broader innovation in Lyme illness diagnostics and remedy.

To obtain all Part 2 updates, subscribe to the LymeX Diagnostics Prize e-newsletter and observe @Lyme_X on Twitter.


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